| ARTICLE |
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| Year : 2009 | Volume
: 14
| Issue : 2 | Page : 85-88 |
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Membranoproliferative glomerulonephritis in a Nigerian adolescent with congenital solitary kidney: Unraveling the cause of mortality
HU Okafor1, SN Uwaezoke1, OC Okafor2
1 Department of Paediatrics, University of Nigeria Teaching Hospital, Ituku-Ozalla, Enugu, Nigeria
2 Department of Morbid Anatomy, University of Nigeria Teaching Hospital, Enugu, Nigeria
Correspondence Address:
S N Uwaezoke
Department of Paediatrics, University of Nigeria Teaching Hospital, Ituku-Ozalla, Enugu
Nigeria
 Source of Support: None, Conflict of Interest: None
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Background: Unilateral renal agenesis (URA) or solitary kidney usually presents as non-ectopic solitary functioning kidney (SFK) with absent contra-lateral kidney. Although it is compatible with normal longevity, recent studies indicate that arterial hypertension, proteinuria, impaired renal function as well as glomerulosclerosis are potential complications.
Case Report: We report a male adolescent patient who presented pre-mortem with features of acute renal failure and lobar pneumonia. Post-mortem examination revealed a solitary kidney with light microscopic findings suggesting membranoproliferative glomerulonephritis (MPGN) as the fundamental disease. The short duration of hospitalization and paucity of diagnostic facilities precluded a more accurate confirmation and classification of the glomerular disease.
This report however highlights possible pathological scenarios, as well as the handicaps in the practice of Nephrology in this environment.
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