• Users Online: 290
  • Print this page
  • Email this page
Year : 2003  |  Volume : 8  |  Issue : 2  |  Page : 17-19

A comparison of Glycosylated Haemoglobin (GHL) in obesity and diabetes mellitus in Enugu metropolis

1 Department of Medical Lab Sciences, UNEC, Enugu, Nigeria
2 Department of Medicine, UNEC, Enugu, Nigeria
3 Department of Dietetics, UNTH, Enugu, Nigeria
4 Department of Chemical Pathology, UNTH, Enugu, Nigeria

Correspondence Address:
J C Onyeanusi
Dept of Medical Lab Sciences, University of Nigeria, Enugu Campus
Login to access the Email id

Source of Support: None, Conflict of Interest: None

Rights and PermissionsRights and Permissions

Aim: To compare the blood concentation of Glycosylated haemoglobin in obesity and diabetes mellitus in Enugu metropolis. Materials and Method: A total of seventy-five patients (male and female) that attended medical Clinic of University of Nigeria Teaching Hospital Enugu were recruited for the study. Fifteen patients were obese, seventeen were obese-diabetics, forty-three were non-obese -diabetics while twenty were non-obese-diabetics with various complications. Twenty apparently healthy subjects served as controls. Fasting blood samples were collected with fluoride-oxalate bottles from both test and control groups. Glycosylated haemoglobin (GHb) and fasting blood sugar (FBG) were determined by the spectrophotometric method while the haematocril (PCV) was determined by microhaematocril method. Results: In obese subjects, the following results were obtained GHb 55.40±3.9 mmol/L fructose, FBG 6.3±1.07 mmol/L, PCV 0.38±0.03 L/L while in obese-diabetics, the following results were recorded GHb 093.45± 6.06 mmol/L fructose, FBG 12.30 ±5.62 mmol/L, PCV 0.39±0.02 L/L. In non-obese-diabetics the results were GHb 95.05. 9mmol/L fructose, FBG 4.90±0.34 mmol/L and PCV 0.41± 0.03 L/L. Statistical comparison of mean results for GHb and FBG showed no significant differences between obese and control groups (P>0.05) while significant differences were recorded between obese-diabetics non-obese diabetics and control groups respectively, (P<0.05). In addition, when the results of the test groups were compared with one another, significant differences were obtained in obese vs non-obese-diabctics (P<0.05) with regard to FBG and GHb. No significant differences were obtained with PCV in all test and control groups. Conclusion: This study has shown that elevated glycosylated haemoglobin and hyperglycemia may not be regular features of obesity whereas they are consistently documented in diabetes.

Print this article     Email this article
 Next article
 Previous article
 Table of Contents

 Similar in PUBMED
   Search Pubmed for
   Search in Google Scholar for
 Related articles
 Citation Manager
 Access Statistics
 Reader Comments
 Email Alert *
 Add to My List *
 * Requires registration (Free)

 Article Access Statistics
    PDF Downloaded58    
    Comments [Add]    

Recommend this journal