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ARTICLE
Year : 2002  |  Volume : 7  |  Issue : 1  |  Page : 54-56

A review of micro albuminuria and its concomitants


Department of Medicine, Ogun State University Teaching Hospital, Sagamu, Nigeria

Correspondence Address:
C O Alebosu
Department of Medicine, Ogun State University Teaching Hospital, P.M.B. 2001, Sagamu
Nigeria
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Source of Support: None, Conflict of Interest: None


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Aim: To collate information on the aetiology, concomitants, pathogenesis and management of micro albuminuria to guide in patient management. Methods: An English language literature search using Medline (1991-2000) was done to assess research/review articles on micro albuminuria. The study design and quality were assessed, with particular attention to subject selection, definition of outcome variables, and applicability of the results to management of patients at risk. Results: Micro albuminuria refers to a urinary albumin excretion of 30-300mg/24hours. Timed collection is the gold standard for research into albuminuria but an albumin: creatinine ratio is sensitive and specific enough. Large variations however occur in urinary albumin excretion rates. Micro albuminuria is associated with systemic hypertension, diabetes mellitus and other clinical states. Microalbuminurics have a higher prevalence of hyperlipidaemia, coronary artery disease, peripheral vascular disease, myocardial infarction and stroke. Conclusions: Many studies have demonstrated the association of microalbuminuria with cardiovascular risk factors. The mechanism of albuminuria and organ damage is still not clear. Anti hypertensives such as angiotensin converting enzyme-inhibitors and calcium channel blockers have a beneficial effects of lowerimg the degree of micro albuminuria.


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