| ARTICLE |
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| Year : 1997 | Volume
: 2
| Issue : 1 | Page : 9-11 |
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Alpha-1-antichymotrypsin levels in apparently normal adult blood donors and in disease conditions
Uchenna Maryann, Obasi, Erasmus Ele, AC J. Ezeoke
Department of Chemical Pathology University Nigeria Teaching Hospital, Enugu, Nigeria
Correspondence Address:
A C J. Ezeoke
Department of Chemical Pathology University of Nigeria, Enugu Campus, Enugu
Nigeria
 Source of Support: None, Conflict of Interest: None
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Serum alpha-l-antichymotrypsin (ACT) levels were determined by single radial immunodiffusion in two hundred (200) apparently healthy blood donors and in one hundred patients with the following diseases - nephrotic syndrome 38, multiple myeloma 30, hepatoma 17, prostatic carcinoma 17 and lymphoma 5. The mean and standard deviation obtained were control 156 ± 71.2 ug/ml, nephrotic syndrome 197.6 ± 112.1 ug/ml, multiple myeloma 220.2 ± 162.4 ug/ml, prostatic carcinoma 465.4 ± 138.1 ug/ml, hepatoma 466.1 ± 143.9 ug/ml and lymphoma 331.2 ± 88.5 ug/ml. When compared with the control these figures were found to be statistically significantly higher (p < 0.0001).
It is possible that the measurement of this acute phase protein could be of prognostic value.
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